Article Text

other Versions

PDF
Drug watch
  1. Kam Uppell
  1. Correspondence to Kam Uppell; kuppell{at}bmjgroup.com

Statistics from Altmetric.com

Perioperative dexamethasone and bleeding in children ­undergoing tonsillectomy

Perioperative dexamethasone administered to children undergoing a tonsillectomy is not associated with excessive, clinically significant bleeding events, according to a study published in JAMA. Explaining the rationale for the study the researchers say that although corticosteroids are commonly given to children during a tonsillectomy to reduce nausea and vomiting there is concern they might increase the risk of perioperative and postoperative haemorrhage.

In a multicentre, double-blind, placebo-controlled study 314 children (aged 3–18 years) were randomised to receive perioperative dexamethasone or placebo. The main outcome was the rate and severity of post-tonsillectomy haemorrhage (using a bleeding severity scale) in the 14 days following surgery. Bleeding events were reported in 17 children (10.8%) in the dexamethasone group and in 13 patients (8.2%) …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.