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Is diuretic use beneficial or harmful for patients with chronic kidney disease?
  1. Yusra Habib Khan1,2,
  2. Azmi Sarriff1,
  3. Tauqeer Hussain Mallhi1,2,
  4. Azreen Syazril Adnan2,
  5. Amer Hayat Khan1
  1. 1Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, University Sains Malaysia, Penang, Malaysia
  2. 2Chronic Kidney Disease Resource Centre, School of Medical Sciences, Health Campus, University Sains Malaysia, Kubang Kerain, Kelantan, Malaysia
  1. Correspondence to Dr Yusra Habib Khan; yusrahabib{at}

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Chronic kidney disease (CKD) is a global health concern that arises as a result of a number of different insults to renal function.1 Progression of CKD to end-stage renal disease is a costly and important clinical event with substantial morbidity.2 Additionally, increase in demand for renal replacement therapy (RRT) makes it important to investigate factors associated with the progression of CKD and the prognosis of earlier stages of CKD.

A retrospective study was conducted of subjects with an estimated glomerular filtration rate (eGFR) between 15 and 59 mL/min/1.73 m2 during a 2-year study period from a hospital database. A total of 621 patients of mean age 61.09±6.57 years were identified. At …

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