| Adverse reaction | Gene | SNP | Genotype | Patients, n (%) | p (Fischer) |
|---|
| Grade 0-I | Grade II-IV |
|---|
|
|---|
| Anaemia | ABCB1 | rs1128503 | T/T-T/C | 26(83.9) | 3(37.5) | 0.016 |
| | | C/C | 5(16.1) | 5(62.5) | |
| | rs2032582 | C/C-C/T | 26(83.9) | 3(37.5) | 0.016 |
| | | T/T | 5(16.1) | 5(62.5) | |
| Neutropenia | NOS3 | rs1799983 | G/G | 7(21.9) | 5(71.4) | 0.013 |
| | | G/T-T/T | 25(78.1) | 2(28.6) | |
| Diarrhoea | NOS3 | rs1799983 | G/G | 7(22.6) | 5(62.5) | 0.035 |
| | | G/T-T/T | 24(77.4) | 3(37.5) | |
| Mucositis | ABCB1 | rs1045642 | T/T | 7(21.2) | 4(66.7) | 0.031 |
| | | T/C-C/C | 26(78.8) | 2(33.3) | |
| | rs1128503 | T/T | 7(21.2) | 4(66.7) | 0.031 |
| | | T/C-C/C | 26(78.8) | 2(33.3) | |
| | rs2032582 | C/C | 7(21.2) | 4(66.7) | 0.031 |
| | | C/T-T/T | 26(78.8) | 2(33.3) | |
| ERCC1 | rs11615 | T/T | 5(15.2) | 4(66.7) | 0.011 |
| | | C/T-C/C | 28(84.8) | 2(33.3) | |