Table 1

Assessment of total time consumption for preprocessing and postprocessing tasks and automated production from two processed runs (run 1 and run 2)

Time (h)Time (h)
Run 1Run 2
Step3 processed drugs (epirubicin, 5-FU, cetuximab)2 processed drugs (gemcitabine, cytarabine)
Release0:04:440:04:11
Create run0:02:150:03:57
Picking of materials0:08:16

  • ▸ 15 infusion bags

  • ▸ 1 empty waste bag

  • ▸ 7 vials

  • ▸ 7 PharmaVent (venting needles)

  • ▸ 3 syringes 60 mL

  • ▸ 3 PharmaNeedle (admixing needles)

 		0:10:23

  • ▸ 15 infusion bags

  • ▸ 13 vials

  • ▸ 13 PharmaVent (venting needles)

  • ▸ 2 syringes 60 mL

  • ▸ 2 PharmaNeedle (admixing needles)

 
Enter lot numbers for materials0:01:470:02:44
Attach bags and vials to holders0:10:520:09:36
Register/weighing step (scale)0:11:020:13:02
Transfer of materials into workbench0:04:430:05:12
Attachment of venting needles to vials0:05:040:04:39
Attachment of admixing needle to syringes0:00:440:00:28
Loading of the device0:05:000:05:00
Total time preprocessing0:54:370:59:12
Unloading of the device0:05:000:05:00
Postprocessing on the scale and labelling0:07:340:07:59
Disconnect holders from bags and vials0:04:520:04:36
Cleaning holders0:02:040:01:57
Total time postprocessing0:19:300:19:32
Total preprocessing and postprocessing tasks1:14:071:18:44
Average admix. vol. per bag38.8 mL47.6 mL
Total production run time of the device0:23:000:34:18

  • 5-FU, 5-Fluorouracil.