Table 1

Stability of dobutamine 500 mg in 50 ml syringes stored under different conditions of temperature, with and without exposure to light

% of initial concentration (mean ±SD, n=3)
Storage conditions3 days7 days14 days21 days28 days35 days42 days
4°C (protected from light)100.02±0.1699.92±0.0999.40±0.1499.36±0.1599.00±0.1798.72±0.1298.26±0.11
Room temperature (protected from light)99.82±0.1699.73±0.1199.21±0.1898.91±0.0598.36±0.1297.70±0.1397.18±0.14
40°C (protected from light)99.75±0.1699.23±0.1698.74±0.0797.81±0.1696.90±0.1696.13±0.1094.92±0.07
Room temperature (exposed to light)99.32±0.1699.10±0.0698.42±0.1398.08±0.1197.74±0.1197.00±0.0696.28±0.16