Formulation | Trade name | Number of studies | Number of patients | Number of years on the market | Patient-days experience | Reference | Score (%) |
---|---|---|---|---|---|---|---|
Sublingual | Abstral | 3 | 123 | >10 | >100 | 61–63 | 57 |
Sublingual | Recivit | 1 | 76 | >10 | >100 | 64 | 53 |
Oromucosal | Actiq | 4 | 296 | >10 | >100 | 59, 65–67 | 62 |
Buccal tablet | Effentora | 3 | 237 | >10 | >100 | 68–70 | 60 |
Buccal film | Breakyl | 1 | 82 | >10 | >100 | 71 | 53 |
Nasal spray | Instanyl | 3 | 235 | >10 | >100 | 59, 60, 72 | 60 |
Nasal spray | PecFent | 4 | 283 | >10 | >100 | 60, 73–75 | 62 |