The stability of four catecholamines in 5% glucose infusions

J Clin Pharm Ther. 1991 Oct;16(5):337-40. doi: 10.1111/j.1365-2710.1991.tb00322.x.

Abstract

The stability of adrenaline, noradrenaline, dopamine and dobutamine in 5% glucose infusion minibags stored at 5 degrees C was determined. Results indicated that noradrenaline (16 and 40 mg/l) and dobutamine (1 and 5 g/l) were relatively stable with t/95% values in excess of 30 days. Adrenaline and dopamine were less stable. The t/95% values were approximately 20 and 14 days respectively.

MeSH terms

  • Catecholamines / administration & dosage
  • Catecholamines / chemistry*
  • Chemistry, Pharmaceutical
  • Dobutamine / administration & dosage
  • Dobutamine / chemistry
  • Dopamine / administration & dosage
  • Dopamine / chemistry
  • Drug Stability
  • Epinephrine / administration & dosage
  • Epinephrine / chemistry
  • Glucose / chemistry*
  • Norepinephrine / administration & dosage
  • Norepinephrine / chemistry
  • Temperature
  • Time Factors

Substances

  • Catecholamines
  • Dobutamine
  • Glucose
  • Dopamine
  • Norepinephrine
  • Epinephrine