Comparing newly obtained and previously known nucleotide and amino-acid sequences
underpins modern biological research. BLAST is a well-established tool for such …

Objectives The aim of this work was to construct InverPep, a database specialised in
experimentally validated antimicrobial peptides (AMPs) from invertebrates. Methods AMP …

Tuberculous meningitis (TBM) is the most lethal form of tuberculosis infection, characterized
by a dysregulated immune response that frequently leads to neurologic injury and death …

Background In July 2013, the European Medicines Agency (EMA) recommended changes to
the use of metoclopramide, including restricting dose (maximum 30 mg/day) and duration …

Background Inappropriate antimicrobial treatment in bloodstream infections is associated
with increased mortality rates and health cost. Purpose To assess the adequacy and …

Background The imiglucerase drug shortages in 2009 forced a change in the treatment of
many patients with Gaucher's disease. Purpose To describe the clinical outcomes of an …

Background Corticosteroids are the standard care in graft-versus-host disease (GVHD).
However, when the condition becomes refractory to steroids, one alternative is the off-label …

Background A safety problem occurred in requesting enteral diets (EDs) in the neonatal unit.
So we decided to develop a special prescription module for requesting EDs. Purpose To …

Background The introduction of newly-approved antiretroviral drugs is leading to changes in
first-line antiretroviral prescription. Purpose To analyse the evolution of antiretroviral …

La diferenciación entre crisis epilépticas y crisis no epilépticas psicógenas (CNEP) en
muchas ocasiones es muy difícil de realizar, dando lugar a un infradiagnóstico de las CNEP …