Discussion This is the first report of compassionate use of HP-β-CD for adult patients over 30
years with NP-C. HP-β-CD infused intrathecally, did not achieve improve or slow disease …

In-tube solid phase microextraction (IT-SPME) coupled on-line to capillary liquid
chromatography with diode array detection provides a simple and fast analytical …

Scedosporium is an important pathogen in cystic fibrosis (CF) and post‐transplantation, but
it rarely causes invasive infection. Treatment remains challenging, particularly due to the …

Niemann-Pick disease type C (NPD-C) is a rare neurodegenerative disorder characterized
by a lysosomal storage disorder. Treatment has been supportive and symptomatic. In animal …

Objective To assess critically oritavancin, a second-generation lipoglycopeptide, for the
treatment of Acute Bacterial Skin and Skin Structure Infections caused by susceptible Gram …

Background Progressive multifocal leukoencephalopathy (PML) is caused by JC virus (JCV)
and has severe consequences for the central nervous system. PML is an opportunistic …

Objective: To assess critically oritavancin, a second-generation lipo-glycopeptide, for the
treatment of Acute Bacterial Skin and Skin Structure Infections caused by susceptible Gram …

Background The increasing prevalence, morbidity and mortality rates of Clostridium difficile
infection (CDI) turn its treatment into a challenge for researchers. Fidaxomicin is a new …

Objetivo: Evaluar críticamente la oritavancina, lipoglicopéptido de segunda generación,
para el tratamiento de la infección bacteriana aguda de la piel y tejidos blandos causada …

Background Cytomegalovirus disease is an important cause of morbidity and mortality in
haematopoietic stem cell transplantation (HSCT) recipients. Foscarnet, an intravenous drug …