Fundamento y objetivo Tras la comercialización de abiraterona, inhibidor de la síntesis de
andrógenos, el objetivo del estudio fue analizar el uso, la respuesta y la seguridad de …

Background Compliance is sometimes difficult for patients treated with temozolomide,
because of the inconvenience due to the high daily number of capsules needed. Studies …

Background and Importance Natalizumab (NTZ) is a monoclonal antibody which targets a
protein called α4β1 integrin on white blood cells involved in inflammation that has …

Background and Importance Immunosuppression due to SARS-CoV2 infection (COVID19)
has caused an increase in identification of multi-resistant organisms in Intensive Care Units …

Background and Importance Obesity is a disease that influences numerous physiological
processes. Currently there is little pharmacokinetic data in obese patients and extrapolated …

Background and Importance Pharmacokinetic monitoring is a tool used in therapeutic
optimisation to achieve the best clinical results and minimise the incidence of adverse …

Background Sunitinib (SU) is an oral, small-molecule, multi-targeted tyrosine kinase
receptor inhibitor that is approved for the treatment of renal cell carcinoma (RCC). However …

Background The approval for the clinical use of direct-acting antivirals in 2011 (boceprevir
[BOC] and telaprevir [TLV], viral NS3 protease inhibitors) has increased recovery rates by up …

Background Previous studies have reported an error rate between 11.7% and 49.0% in the
medication process for hospitalised children. Off-label use and diluting medicines increase …

Background Brentuximab is a monoclonal antibody targeting CD30 receptors, authorised in
2011 by FDA for the treatment of Hodgkin's lymphoma and other lymphomas refractory to …