Morphine is a potent opioid analgesic widely used for the treatment of acute pain and for
long‐term treatment of severe pain. Morphine is a member of the morphinan‐framed …

Clinical studies comparing the response and side effects of various opioids have not been
able to show robust differences between drugs. Hence, recommendations of the regulatory …

Much evidence points to the involvement of N-methyl-d-aspartate (NMDA) receptors in the
development and maintainance of neuropathic pain. In neuropathic pain, there is generally …

The finding affinities of racemic methadone and its optical isomers R-methadone and S-
methadone were evaluated for the opioid receptors mu 1, mu 2, delta and kappa, in …

Poorly controlled pain is a global public health issue. The personal, familial and societal
costs are immeasurable. Only a minority of European patients have access to a …

Visceral pain can be difficult to treat with classical μ-opioid agonists and it has been
suggested to use opioids with distinct pharmacological profiles. In animal experiments …

Aim: The aim of the study was to investigate the swallow ability and the patient preferences
of tablets and capsules with different sizes, shapes, surfaces and colours. Method: Patients …

Morphine is a widely used opioid for treatment of moderate to severe pain, but large
interindividual variability in patient response and no clear guidance on how to optimise …

The indication for morphine use is primarily pain, but also a combined analgesic and
sedative effect may be the rationale behind morphine administration. Paediatric morphine …

The aim of the study was to investigate the influence of pain, sedation, pain medications and
socio-demographics on cognitive functioning in chronic non-malignant pain patients …