User profiles for "author:M Peak"

Peak M

Alder Hey Children's NHS Foundation Trust
Verified email at alderhey.nhs.uk
Cited by 3498

[HTML][HTML] Chromatin architecture and the generation of antigen receptor diversity

S Jhunjhunwala, MC van Zelm, MM Peak, C Murre - Cell, 2009 - cell.com
The adaptive immune system generates a specific response to a vast spectrum of antigens.
This remarkable property is achieved by lymphocytes that each express single and unique …

Effects of UV radiation on cells

J Moan, MJ Peak - Journal of Photochemistry and Photobiology B: Biology, 1989 - Elsevier
UV radiation interacts with mammalian cells in a very complex manner, although DNA
appears to be the main chromophore. Recent literature within this field is reviewed. The …

Magnetic order and phase transformation in Ni2MnGa

PJ Webster, KRA Ziebeck, SL Town… - Philosophical …, 1984 - Taylor & Francis
Magnetization, magnetic susceptibility, optical microscopy, X-ray diffraction and neutron
diffraction measurements have been made on a quenched sample of Ni2MnGa. Room …

A systematic review of the use of dosage form manipulation to obtain required doses to inform use of manipulation in paediatric practice

…, UU Shah, JL Ford, CE Barker, M Peak… - International journal of …, 2017 - Elsevier
This study sought to determine whether there is an evidence base for drug manipulation to
obtain the required dose, a common feature of paediatric clinical practice. A systematic …

[HTML][HTML] The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions

S Jhunjhunwala, MC van Zelm, MM Peak, S Cutchin… - Cell, 2008 - cell.com
The immunoglobulin heavy-chain (Igh) locus is organized into distinct regions that contain
multiple variable (VH), diversity (DH), joining (JH) and constant (CH) coding elements. How …

[HTML][HTML] Adverse drug reactions and off-label and unlicensed medicines in children: a nested case? Control study of inpatients in a pediatric hospital

…, LE Bracken, HL Mannix, KA Bird, JC Duncan, M Peak… - BMC medicine, 2013 - Springer
Background Off-label and unlicensed (OLUL) prescribing has been prevalent in pediatric
practice. Using data from a prospective cohort study of adverse drug reactions (ADRs) …

3D printed oral theophylline doses with innovative 'radiator-like'design: Impact of polyethylene oxide (PEO) molecular weight

A Isreb, K Baj, M Wojsz, M Isreb, M Peak… - International journal of …, 2019 - Elsevier
Despite the abundant use of polyethylene oxides (PEOs) and their integration as an
excipient in numerous pharmaceutical products, there have been no previous reports of …

[HTML][HTML] Manipulation of drugs to achieve the required dose is intrinsic to paediatric practice but is not supported by guidelines or evidence

RH Richey, UU Shah, M Peak, JV Craig, JL Ford… - BMC pediatrics, 2013 - Springer
Background A lack of age-appropriate formulations can make it difficult to administer
medicines to children. A manipulation of the dosage form may be required to achieve the …

[HTML][HTML] Incidence, characteristics and risk factors of adverse drug reactions in hospitalized children–a prospective observational cohort study of 6,601 admissions

…, KA Bird, JC Duncan, L Cresswell, JJ Kirkham, M Peak… - BMC medicine, 2013 - Springer
Abstract Background Adverse drug reactions (ADRs) are an important cause of harm in
children. Current data are incomplete due to methodological differences between studies …

Photosensitized production of superoxide anion by monochromatic (290–405 nm) ultraviolet irradiation of NADH and NADPH coenzymes

ML Cunningham, JS Johnson… - Photochemistry and …, 1985 - Wiley Online Library
The reduced pyridine coenzymes NADPH and NADH produced superoxide anion (“CK”)
from ground state molecular oxygen when irradiated by ultraviolet (UV) radiation extending …