The potential of siRNA based drug delivery in respiratory disorders: Recent advances and progress
Lung diseases are the leading cause of mortality worldwide. The currently available
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …
therapies are not sufficient, leading to the urgent need for new therapies with sustained anti …
[HTML][HTML] Endoplasmic reticulum stress and oxidative stress: a vicious nexus implicated in bowel disease pathophysiology
The endoplasmic reticulum (ER) is a complex protein folding and trafficking organelle.
Alteration and discrepancy in the endoplasmic reticulum environment can affect the protein …
Alteration and discrepancy in the endoplasmic reticulum environment can affect the protein …
[HTML][HTML] Smoking and COVID-19: What we know so far
The ongoing COVID-19 pandemic has placed a spotlight on infectious diseases and their
associations with host factors and underlying conditions. New data on the Severe Acute …
associations with host factors and underlying conditions. New data on the Severe Acute …
[HTML][HTML] Role of oxidative stress in the pathology and management of human tuberculosis
Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, is the leading
cause of mortality worldwide due to a single infectious agent. The pathogen spreads …
cause of mortality worldwide due to a single infectious agent. The pathogen spreads …
[HTML][HTML] Gut microbial changes, interactions, and their implications on human lifecycle: an ageing perspective
R Vemuri, R Gundamaraju, MD Shastri… - BioMed research …, 2018 - hindawi.com
Gut microbiota is established during birth and evolves with age, mostly maintaining the
commensal relationship with the host. A growing body of clinical evidence suggests an …
commensal relationship with the host. A growing body of clinical evidence suggests an …
Increasing complexity and interactions of oxidative stress in chronic respiratory diseases: an emerging need for novel drug delivery systems
Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …
An overview of vaccine development for COVID-19
SH Shahcheraghi, J Ayatollahi, AAA Aljabali… - Therapeutic …, 2021 - Future Science
The COVID-19 pandemic continues to endanger world health and the economy. The
causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the …
causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the …
[HTML][HTML] Multi-drug resistant Mycobacterium tuberculosis & oxidative stress complexity: Emerging need for novel drug delivery approaches
Tuberculosis (caused by Mycobacterium tuberculosis, Mtb) treatment involves multiple drug
regimens for a prolonged period. However, the therapeutic benefit is often limited by poor …
regimens for a prolonged period. However, the therapeutic benefit is often limited by poor …
The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders
WC Chong, MD Shastri, GM Peterson… - Clinical & …, 2021 - Wiley Online Library
Inflammation is the result of a complex network of cellular and molecular interactions and
mechanisms that facilitate immune protection against intrinsic and extrinsic stimuli …
mechanisms that facilitate immune protection against intrinsic and extrinsic stimuli …
Probiotic Bacillus coagulans MTCC 5856 spores exhibit excellent in-vitro functional efficacy in simulated gastric survival, mucosal adhesion and immunomodulation
Probiotic Bacillus coagulans MTCC 5856 spores were evaluated in-vitro for their ability to
survive simulated digestion, adhesion to colonic cells and immunomodulatory properties …
survive simulated digestion, adhesion to colonic cells and immunomodulatory properties …