User profiles for "author:de Almagro"

Dr. María Martín de Almagro

University of Ghent
Verified email at ugent.be
Cited by 474

The inhibitor of apoptosis (IAP) proteins are critical regulators of signaling pathways and targets for anti-cancer therapy

MC De Almagro, D Vucic - Experimental oncology, 2012 - dspace.nbuv.gov.ua
Cell death regulation is vital for maintenance of homeostasis and proper development of
multicellular organisms. Inhibitor of apoptosis (IAP) proteins are implicated in multiple ways …

Necroptosis: Pathway diversity and characteristics

MC de Almagro, D Vucic - Seminars in cell & developmental biology, 2015 - Elsevier
Regulated cell death is a physiological process that controls organismal homeostasis.
Deregulation of cell death can lead to the development of a number of human diseases and …

Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis

…, DL Dugger, KE Wickliffe, N Kapoor, MC de Almagro… - Science, 2014 - science.org
Receptor-interacting protein kinase 1 (RIPK1) and RIPK3 trigger pro-inflammatory cell death
termed “necroptosis.” Studies with RIPK3-deficient mice or the RIPK1 inhibitor necrostatin-1 …

[HTML][HTML] Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death

MC de Almagro, T Goncharov… - Cell Death & …, 2017 - nature.com
Proper regulation of cell death signaling is crucial for the maintenance of homeostasis and
prevention of disease. A caspase-independent regulated form of cell death called …

Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colon cancer: a phase 3 randomized clinical trial

…, AM López, C Villar, CGM de Almagro… - JAMA …, 2023 - jamanetwork.com
Importance Peritoneal metastasis in patients with locally advanced colon cancer (T4 stage)
is estimated to recur at a rate of approximately 25% at 3 years from surgical resection and is …

[HTML][HTML] Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination

MC de Almagro, T Goncharov, K Newton… - Cell death & disease, 2015 - nature.com
Necroptosis is a caspase-independent regulated type of cell death that relies on receptor-
interacting protein kinases RIP1 (receptor-interacting protein kinases 1) and RIP3. Tumor …

OTUB1 modulates c‐IAP1 stability to regulate signalling pathways

T Goncharov, K Niessen, MC De Almagro… - The EMBO …, 2013 - embopress.org
The cellular inhibitor of apoptosis (c‐IAP) proteins are E3 ubiquitin ligases that are critical
regulators of tumour necrosis factor (TNF) receptor (TNFR)‐mediated signalling. Through …

[HTML][HTML] Effects of collection and processing procedures on plasma circulating cell-free DNA from cancer patients

…, DWY Tsui, H Biggs, ARVM de Almagro… - The Journal of Molecular …, 2018 - Elsevier
Circulating tumor DNA (ctDNA) offers new opportunities for noninvasive cancer
management. Detecting ctDNA in plasma is challenging because it constitutes only a minor …

Producing participants: Gender, race, class, and women, peace and security

M Martín de Almagro - Global Society, 2018 - Taylor & Francis
Recent efforts to implement the Women, Peace and Security (WPS) agenda and the creation
of National Action Plans (NAPs) in post-conflict countries have resulted in a set of …

Lost boomerangs, the rebound effect and transnational advocacy networks: A discursive approach to norm diffusion

MM De Almagro - Review of International Studies, 2018 - cambridge.org
This article aims to show the added value of studying transnational advocacy networks
through a discursive approach in order to better understand the outcomes of norm diffusion …