The emergence of carbapenemase-producing Enterobacterales (CPE) as a major cause of
invasive infection both within the UK and internationally poses a very real concern for all …

Background Falls are a common cause of morbidity and hospitalisation in older people.
Inappropriate prescribing and polypharmacy contribute to falls risk in elderly patients. This …

The Comment by Paul Verweij and colleagues1 on diagnosing COVID-19-associated
pulmonary aspergillosis was insightful and much needed. We note some unanswered …

Background Penicillin allergy labels are commonly acquired in childhood and lead to
avoidance of first-line penicillin antibiotics. Understanding the health outcomes of penicillin …

Background With increasing frequency of resistant Gram-negative bacteria, temocillin has
potential utility in reducing carbapenem use. The 2020 EUCAST guideline changes …

Background Antimicrobial resistance (AMR) is an ecological and economic crisis and
stewardship of available antimicrobials is required. Electronic prescribing, where available …

Incompatibility poses a constant risk when mixing medicines but it can be avoided by
understanding the chemical reactions taking place. In the image, a group of IV drips in …

Background Acute kidney injury (AKI) is a potential complication of systemic infection.
Optimizing antimicrobial dosing in this dynamic state can be challenging with sub-or supra …

Introduction The glycopeptide teicoplanin is commonly utilized to facilitate outpatient
parenteral antimicrobial therapy (OPAT). Licensed for once daily maintenance dosing …

Background Tigecycline has potential utility in the treatment of complex polymicrobial
infections or those caused by MDR organisms in the ambulatory care setting owing to its …