Article Text

Download PDFPDF
Technology (including: robots for production, Incompatibilities, drug production and analytics, CRS)
Batch or named-patient preparation: introduction of a decision algorithm
  1. M. Grouzmann,
  2. S. Lamon,
  3. G. Podilsky,
  4. A. Pannatier
  1. 1Pharmacy Department, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
  2. 2School of Pharmaceutical Sciences, University of Geneva University of Lausanne, 1211 Geneve 4, Switzerland


Background One of the tasks of the Pharmacy Department of the CHUV (Centre Hospitalier Universitaire Vaudois) is to supply the hospital with drugs. Medicines not commercially available must be manufactured by the pharmacy. This can be done batch-wise or through named prescriptions for individual patients.

Purpose Batch manufacturing implies a number of principles and constraints such as planning, delays to be taken into account, number of items per batch, final check by the Quality Control Unit and storage and distribution by the Pharmaceutical Logistics Unit. Because these are often incompatible with personalised medicine, it was necessary to define criteria allowing the Manufacturing Unit to decide between batch and individual preparation.

Materials and methods Three pharmacists collaborated to design and develop a decision algorithm meeting the above objective. This algorithm was then introduced and is being applied to all preparations manufactured by the Pharmacy Division.

Results The following criteria were taken into account when designing the algorithm: standardised doses, stability, frequency and number of prescriptions, urgency and costs. A total of 440 preparations were analysed according to the algorithm; 174 have been earmarked for batch production and 266 for named-patient preparation.

Conclusions This algorithm now provides the Manufacturing Unit with an objective tool with which to decide between batch-wise and named-patient classification for new preparations and to review the status of preparations annually.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.