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GRP-183 The Effect of a Clinical Pharmacist-Led Training Programme on Intravenous Preparation and Administration Errors in a Vietnamese Hospital
  1. HT Nguyen1,
  2. TD Nguyen2,
  3. ER van den Heuvel3,
  4. FM Haaijer-Ruskamp4,
  5. K Taxis1
  1. 1University of Groningen, Pharmacotherapy & Pharmaceutical Care, Groningen, The Netherlands
  2. 2University of Medicine and Pharmacy at Ho Chi Minh city, Clinical Pharmacy, Ho Chi Minh, Vietnam
  3. 3University Medical Center Groningen, Epidemiology, Groningen, The Netherlands
  4. 4University Medical Center Groningen, Clinical Pharmacology, Groningen, The Netherlands


Background Medication safety has been a concern for decades worldwide, but there is still relatively little research about interventions to reduce medicines administration errors in hospitals, especially in resource-restricted settings such as Vietnam. Our large study on the frequency and type of medication errors in Vietnamese hospitals indicated that the highest risk was associated with intravenous medication administration [1].

Purpose To investigate the effect of intensive training on the frequency of intravenous medicines preparation and administration errors in an urban public hospital in Vietnam.

Materials and Methods This was a controlled intervention study with pre- and post-intervention measurements using a direct observation method, carried out in two critical care units: Intensive Care Unit (ICU – intervention ward), and Post-Surgical Unit (PSU – control ward). The intervention consisted of lectures plus practical ward-based teaching sessions, carried out by a clinical pharmacist and a nurse. In each ward, all intravenous doses prepared and administered by nurses were observed 12 hours per day, on 7 consecutive days, each period.

Results A total of 1294 doses were observed, 718 in ICU and 576 in PSU. Error rate on the intervention ward (ICU) decreased from 62.7% to 52.5% (P = 0.01); preparation errors including wrong dose, deteriorated drug, wrong technique of preparation decreased significantly (p < 0.05). On the control ward (PSU) there was no significant change in error rates (73.8% vs. 73.1%, p = 0.85); almost all preparation error types were similar in both periods (p > 0.05), except for technique errors, which was increased from 15.5% to 25.9% (p < 0.05).

Conclusions Intensive training showed a slight improvement in overall and specific error rates, particularly preparation errors. Further measures are needed to improve patient safety.


  1.  EAHP abstract titled: “Errors in medication preparation and administration in Vietnamese hospitals”, by H.T. Nguyen et al,

No conflict of interest.

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