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DI-007 Assessment of the effect of patient education on compliance with antibiotic treatment in ambulatory patients
  1. M Ormeci1,
  2. C Macit2,
  3. O Kocaagaoglu1,
  4. S Yalcin1,
  5. I Gunaydin1,
  6. F Yoldas1,
  7. A Uygun1,
  8. G Guveneroglu1
  1. 1Yeditepe University, Faculty of Pharmacy, Istanbul, Turkey
  2. 2Yeditepe University, Faculty of Pharmacy, Pharmacology, Istanbul, Turkey


Background Compliance has a crucial role for better therapeutic outcomes. Patient education correlates with compliance because informed patients are more conscious of their medicines. Many studies have highlighted the importance of taking antibacterial agents properly.

Purpose To evaluate the effect of patient education on compliance with prescribed antibacterial agents.

Material and methods A prospective, controlled trial was performed with 99 and 100 participants in a study group (better informed and educated) and control group (basic information), respectively. Participants completed a two-part questionnaire. The first part recorded socio-demographical info, diagnosis and details of prescribed antibiotics of the patients. The second part was presented one day after the end of the treatment. To measure the non-compliance, questions were asked about the number of pills remaining in blisters or containers, omitting the treatment or missing a dose, at what time patient took the drugs, feeling better or not and whether the patient leaflet had been read. Non-compliance was assessed both objectively using “tablet count” and subjectively using a “self-report”.

Results The non-compliance rate was found to be statistically significantly higher in the control group compared to the study group (p < 0.05). Patients in the study group educated by a pharmacist did not quit antibiotic treatment (p < 0.05). Patients who reported not having recovered from their infection were more commonly observed in the control group (p < 0.05). Patients who used antibiotics at the right dose and time were also more numerous in the study group than the control group. There was a significant difference between study and control group in terms of age, with a younger study group.

Conclusion Higher compliance rates with antibacterial treatment and improved clinical outcomes were found in the study group.


  1. Cals JW, Hopstaken RM, Le Doux PH, et al. Dose timing and patient compliance with two antibiotic treatment regimens for lower respiratory tract infections in primary care. Int J Antimicrob Agents 2008;31:531–6

  2. Kardas P. Patient compliance with antibiotic treatment for respiratory tract infections. J Antimicrob Chemother 2002;49:897–903

ReferencesNo conflict of interest.

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