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Section 6: Education and research
6ER-003 Blind comparative study in telangiectasias and reticular veins treatment with nd:yag laser and sclerotherapy
  1. MN Obloja1,
  2. S Ianosi2,
  3. D Neagoe3,
  4. DC Calina1,
  5. OA Docea1,
  6. G Ianosi4,
  7. O Zlatian5
  1. 1University of Medicine and Pharmacy, Faculty of Pharmacy, Craiova, Romania
  2. 2County Clinical Emergency Hospital of Craiova Romania, Dermatology, Craiova, Romania
  3. 3County Clinical Emergency Hospital of Craiova Romania, Internal Medicine, Craiova, Romania
  4. 4County Clinical Emergency Hospital of Craiova Romania, Surgery, Craiova, Romania
  5. 5University of Medicine and Pharmacy, Microbiology, Craiova, Romania

Abstract

Background Telangiectasias and reticular veins of the lower extremities are common lesions. Sclerotherapy was considered the gold standard for treatment. The aim of our study was to evaluate the efficacy and safety of hypertonic 20% saline/2% lignocaine (HS) and polidocanol 0.5% (POL) compared with laser clinical results.

Purpose This is a prospective, randomised study comparing the efficacy of sclerotherapy with POL, HS and long-pulsed neodymium ytrium aluminium garnet (Nd:YAG) laser in the treatment of legtelangiectasias in females, using each patient as her own control.

Material and methods We included in this study 285 females with primary leg telangiectasias and reticular veins (C 1A E p A S1 P N) in order to be treated with sclerotherapy or laser. One leg was treated with one of: Nd:YAG, POL or HS. The others receive, randomly, one other of these treatments. At the end there were 190 legs treated with each method. There were two sessions at 8 weeks’ interval. Assessment of vessels clearing, patient satisfaction and complications was conducted after 2 months: patient’s satisfaction, treating physician’s evaluation and blinded physician’s evaluation. Two investigator and #39;s evaluation was made using before and after photographs of the leg vessels using a 6-point scale from 0 (no change) to 5 (100% cleared). Patients reported pain sensation and outcome satisfaction.

Results Regarding patient satisfaction, we noted no statistical significant differences (P 0.72), but group Nd:YAG felt that treatment was more painful (P 0.003). Physicians’ result assessment proved no statistically significant difference between HS, Nd:YAG and POL-treated legs. POL and HS caused more staining compared with Nd:YAG (P 0.02 and 0.03).

Conclusion Regarding patient satisfaction, we noted no statistical significant differences (P 0.72), but groupNd:YAG felt that treatment was more painful (P 0.003). Physicians’ result assessment proved no statistically significant difference between HS, Nd:YAG and POL-treated legs. POL and HS caused more staining compared with Nd:YAG (P 0.02 and 0.03).

References and/or Acknowledgements We gratefully thank all the staff of our medical centre for supporting this study.

No conflict of interest

http://dx.doi.org/10.1136/ejhpharm-2018-eahpconf.496

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