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High-dose quetiapine and therapeutic monitoring
  1. Hervé Javelot1,
  2. Francis Rangoni2,
  3. Luisa Weiner3,
  4. Bruno Michel4
  1. 1 Service de Pharmacie Clinique, Etablissement Public de Santé Alsace Nord, Brumath, France
  2. 2 Pôle G07, Etablissement Public de Santé Alsace Nord, Brumath, France
  3. 3 Psychiatry II, Civil Hospital, CHU Strasbourg, Strasbourg, France
  4. 4 Service de Pharmacie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France
  1. Correspondence to Dr Hervé Javelot, Service Pharmacie, Etablissement Public de Santé Alsace Nord, Brumath 67170, France; herve.javelot{at}


Quetiapine is an atypical antipsychotic with a good safety profile permitting its administration beyond the maximum dose of 800 mg/day. We report the case of a patient with a resistant schizophrenia treated with high doses of quetiapine (up to 2000 mg/day) combined with drug monitoring and with favourable therapeutic response and tolerance.

  • psychiatry
  • therapeutic drug monitoring
  • antipsychotics
  • quetiapine
  • resistant schizophrenia

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