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YH and WL contributed equally.
Contributors YH and DL contributed to the conception and design of the study, had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. YH contributed to the acquisition of data. YH and DL contributed to the analysis and interpretation of the data. WL contributed to the statistical analyses. All authors participated in manuscript writing, revision, and approval for final submission. YH and WL contributed equally and share first authorship.
Funding This work was financially supported by the National Natural Science Foundation of China (No. 81803387), and the Hubei Provincial Natural Science Foundation of China (No. 2018CFB152).
Competing interests None declared.
Patient consent for publication Not required.
Ethics approval This study was approved by the Ethics Commission of Tongji Hospital (TJ-C20200123).
Provenance and peer review Not commissioned; internally peer reviewed.