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2SPD-021 Survey of drug shortages in Hungarian hospitals
  1. RG Vida1,
  2. S Sebők2,
  3. B Nyaka1,
  4. J Hornyák1,
  5. L Botz1
  1. 1University of Pécs Faculty of Pharmacy, Department of Pharmaceutics and Central Clinical Pharmacy, Pécs, Hungary
  2. 2Semmelweis University, University Pharmacy Department of Pharmacy Administration, Budapest, Hungary


Background and importance Drug shortages pose an enormous challenge to healthcare systems globally. However, the data available are limited, as there are 53 surveys in the literature and only 54.7% (29) contain any information regarding the prevalence of drug supply issues.

Aim and objectives Our aim was to develop a questionnaire based on the available surveys and collect evidence of drug shortages in Hungarian hospitals.

Material and methods With an extensive literature search between 1 and 15 April 2019, we identified the relevant surveys and questionnaires, and then developed a Hungarian version with 45 questions categorised into 5 main sections: (1) institutional data and demographics; (2) prevalence and background; (3) management of drug shortages; (4) information sources; and (5) consequences of drug shortages. Data were collected between 15 May and 30 June 2019, with an online survey among hospital pharmacists.

Results A total of 42 hospital pharmacist completed the survey: 36 women and 6 men, mainly >36 years of age (73.8%), from various institutions and scope of activities. We found that 52.4% experienced drug shortages more than 10 times in the past 6 months. The top five ATC groups included B (blood and blood forming organs (52.4%)), C (cardiovascular system (50%)), L (antineoplastic and immunomodulating agents (47.6%)), J (anti-infectives for systemic use (38.1%)) and N (nervous system (38.1%)). Active pharmaceutical ingredients highlighted were immunoglobulins, digoxin, sodium ferric gluconate, phytomenadione, idarubicin and amoxicillin/clavulanic acid. Original and generic drugs, and parenteral and oral dosage forms were equally affected. According to 53.7% of participants, drug shortage situations usually lasted for months. The main reasons noted were manufacturing problems (66.7%), tendering processes (54.8%) and raw material supply problems (52.4%). Serialisation was also mentioned (16%) as a cause of drug shortages.

Conclusion and relevance This is the first time a drug shortage survey focusing on Hungary has been completed. The data and tendencies collected were mainly in accordance with results of previous surveys and global tendencies. However, a new finding is that drugs belonging to ATC group B were affected the most by supply disruptions in Hungary. In addition, this is the first time that serialisation was linked with drug shortages in a survey.

References and/or acknowledgements No conflict of interest.

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