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SARS-COV-2 pandemic: establishing three risk levels for 19 Italian regions and two autonomous provinces
  1. Andrea Messori1,
  2. Manuela Angileri2,
  3. Marco Chiumente3,
  4. Laura Agnoletto4,
  5. Paolo Baldo5,
  6. Laura Bartoli1,
  7. Mario Cirino6,
  8. Vera Damuzzo7,
  9. Elisa Ferracane1,
  10. M Cecilia Giron8,
  11. Carolina Laudisio9,
  12. Daniele Mengato10,
  13. Angelo Claudio Palozzo11,
  14. Sabrina Trippoli12
  1. 1 HTA Unit, Regione Toscana, Firenze, Toscana, Italy
  2. 2 Hospital Pharmacy, Azienda Sanitaria di Firenze, Firenze, Toscana, Italy
  3. 3 Scientific Direction, SIFaCT, Milan, Italy
  4. 4 Hospital Pharmacy, Azienda ULSS 5 Polesana, Rovigo, Veneto, Italy
  5. 5 Hospital Pharmacy, Centro di Riferimento Oncologico, Aviano, Italy
  6. 6 Hospital Pharmacy, Azienda Sanitaria Universitaria Giuliano Isontina, Presidio Ospedale Maggiore, Trieste, Italy
  7. 7 Pharmaceutical Sciences, Universita degli Studi di Padova, Padova, Veneto, Italy
  8. 8 Department of Pharmaceutical Sciences, Universita degli Studi di Padova, Padova, Veneto, Italy
  9. 9 Pharmacy, Azienda Sanitaria Locale Salerno, Salerno, Campania, Italy
  10. 10 Hospital Pharmacy, Bolzano Hospital, Bolzano, Italy
  11. 11 Presidency, SIFaCT President, Italian Society for Clinical Pharmacy and Therapy, Milano, Milano, Italy
  12. 12 HTA Unit, Regional Health Service, Firenze, Italy
  1. Correspondence to Dr Andrea Messori, HTA Unit, Regione Toscana, 50129 Firenze, Toscana, Italy;{at}

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In Italy, there are 19 regions and two autonomous provinces, and each of these 21 jurisdictions has local responsibility for health care. As regards the COVID-19 pandemic, these 21 jurisdictions have been classified into three classes of risk (mild, moderate, and high) associated with three colours (green/yellow, orange, and red).

More than 20 indicators are routinely collected in these jurisdictions, and this information determines, every 2 weeks, the colour assigned and the consequent restrictions in everyday life. The replicability index (Rt according to the Italian notation) is the main parameter influencing this decision.

In November 2020, a number of health care professionals began a collaboration (based on a Facebook group named PIFO including 446 people) specifically aimed at discussing topics and controversies in the field of COVID-19.1 A total …

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  • Contributors All authors contributed equally to this paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.