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4CPS-198 The impact of a pharmacist-led medication review on the medicine risk score: a non-randomised controlled study
  1. C Olesen,
  2. EH Hosbjerg
  1. Hospital Pharmacy Central Denmark Region, Clinical Pharmacy, Aarhus N, Denmark


Background and importance Multiple studies have shown that pharmacist-led medication reviews can reduce and prevent drug-related problems. Medication reviews require great economic resources and, consequently, the pharmacists need to prioritise the patients who would benefit the most from a medication review. A group of researchers have designed an algorithm called Medicine Risk Score (MERIS) to identify patients who are at increased risk of experiencing medication errors.1 Even though the algorithm has been used regularly in the selection of patients for medication review, the impact on the patients’ MERIS-scores has not yet been investigated.

Aim and objectives To investigate the impact of a pharmacist-led medication review on the MERIS-score for hospitalised patients.

Material and methods In a controlled, prospective study the MERIS-scores for patients who underwent a pharmacist-led medication review (intervention group – Hospital A) were compared with the MERIS-scores for patients who did not undergo a medication review (control group – Hospital B). Additionally, it was investigated to what extend a change in the MERIS-score was related to the drug-related problems identified. Participants: patients without a medication review in recent months and a MERIS score ≥14, admitted to a medical or cardiology department at two local hospitals. Primary outcome: change in MERIS-scores calculated as the difference in MERIS-score before medication review and 1½ days after.

Results A total of 54 patients were included in the intervention group and 162 patients in the control group. By comparing the changes in the MERIS-scores, no statistically significant difference between the two groups was observed (p=0.84). Of the drugs included in the identified drug-related problems, slightly over 50% had a potential risk of harm or interaction, which influenced the MERIS-score. However, only 17.2% of the drugs would, if the recommendations were implemented, lead to changes in the MERIS-scores.

Conclusion and relevance A pharmacist-led medication review does not seem to have an impact on the MERIS-score for hospitalised patients. Further studies are needed to identify interventions that can reduce patient risk of medication errors.

References and/or acknowledgements 1. Saedder EA, et al. Detection of patients at high risk of medication errors: development and validation of an algorithm. Basic Clin Pharmacol Toxicol 2016;118(2):143–149.

Conflict of interest No conflict of interest

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