Article Text

Download PDFPDF
Medicine shortages in the hospital setting: analysis of the trend in five Italian centres during the three waves of the SARS-CoV-2 pandemic
  1. Ludovica Mazzoleni1,2,
  2. Andrea Zovi1,2,
  3. Cecilia Borsino1,
  4. Cinzia D'Angelo1
  1. 1 UOC Farmacia, ASST Santi Paolo e Carlo, Milano, Italy
  2. 2 Department of Pharmaceutical Sciences, Università degli Studi di Milano, Milano, Italy
  1. Correspondence to Dr Ludovica Mazzoleni, UOC Farmacia, ASST Santi Paolo e Carlo, 20142 Milano, Italy; lmazzo2004{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

In recent years the phenomenon of medicine shortages has increased worldwide, resulting in serious difficulties for healthcare professionals in ensuring access to treatment for patients.1 2 During the SARS-CoV-2 pandemic, the phenomenon was further exacerbated by the massive consumption of specific medicines with consequent shortages due to production-related problems.3 The issue has been addressed by identifying overlapping alternative therapies, or by importation or even by making extemporaneous substitute preparations.4 At the centres run by our regional health authority (two hospitals and three prisons), an analysis was conducted to assess the trend in the phenomenon in the three waves of the pandemic, considering medicines included in the therapeutic formulary (TF). The aim of the research was to determine the daily impact of the …

View Full Text


  • Author Contributions: Ludovica Mazzoleni (L.M.), Andrea Zovi (A.Z.), Cecilia Borsino (C.B.), Cinzia D'Angelo (C.D.) Conceptualization, L.M. and A.Z.; methodology, A.Z.; investigation, L.M. and A.Z.; writing—original draft preparation, L.M. and A.Z.; writing—review and editing, A.Z. and C.D.; visualization, C.B. and C.D.; supervision, C.D. All authors have read and agreed to the published version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.