Footnotes

• Author Contributions: Ludovica Mazzoleni (L.M.), Andrea Zovi (A.Z.), Cecilia Borsino (C.B.), Cinzia D'Angelo (C.D.) Conceptualization, L.M. and A.Z.; methodology, A.Z.; investigation, L.M. and A.Z.; writing—original draft preparation, L.M. and A.Z.; writing—review and editing, A.Z. and C.D.; visualization, C.B. and C.D.; supervision, C.D. All authors have read and agreed to the published version of the manuscript.

• Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

• Competing interests None declared.

• Provenance and peer review Not commissioned; internally peer reviewed.