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5PSQ-128 Thromboprophylaxis in the emergency department. adequacy of the prescription
  1. A Jofré,
  2. JI Bretones,
  3. M Herrera Expósito,
  4. J Urda Romacho,
  5. MÁ Castro Vida,
  6. J Canto-Mangana
  1. Hospital Universitario De Poniente, Hospital Pharmacy, El Ejido, Spain


Background and Importance In Europe, the VITAE study estimates an annual incidence of venous thromboembolic disease (VTD) of 243/100,000 inhabitants.

About 25% of VTD cases are related to hospital admissions and 50–75% of VTD cases occur in non-surgical hospitalised patients. PRETEMED is a validated thrombotic risk (TR) scale for clinical prediction that have been designed to be used in daily clinical practice. As well, it is recommended to assess the bleeding risk (BR) with another validated scale called IMPROVE scale before starting thromboprophylaxis (TP).

Aim and Objectives Determine the (TR/BR) and analyse whether the prescription of thromboprophylaxis in patients from the Emergency Department who are going to be admitted to the hospital ward is adequate.

Material and Methods Prospective observational cohort study, carried out in a 2nd level hospital during a period of 10 days. Adult patients in the ED awaiting admission to the hospital ward were included.

Patients with therapeutic effort limitation, COVID-19 patients, those who had been transfused in the last 48 hours, bleeding patients or those with underlying pathology that require anticoagulation were excluded. Using the PRETEMED/IMPROVE scales, the TR/BR was determined, as well as the indication of thromboprophylaxis.

Results 62 patients. 31 women (50%). The median age [range] was 71 [18–93] years. 31 patients with TP regimen, no interventions had to be performed, they had an adequate indication with PRETEMED> 4 and IMPROVE <7. 31 patients without TP regimen; 7 (23%) of them had indication for TP and they went into the operating room with PRETEMED> 4 and IMPROVE <7. 7 (11.3%) of the patients required pharmaceutical intervention to adequate their TP, all of them by default.

Conclusion and Relevance The prescription of TP in adults who visit the ED could be considered adequate in a high percentage, however it can be optimised according to the PRETEMED and IMPROVE guidelines. It is essential to recommend on the use of scales that assess TR/BR for the correct decision-making in the prescription of TP. The limitation of the study was the small sample size.

Conflict of Interest No conflict of interest

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