Background and Importance Despite its apparent benefits, electronic prescribing systems still face numerous challenges. Without effective electronic communication between prescribers and pharmacists, medication may be dispensed incorrectly, resulting in patient harm.

Aim and Objectives To determine potential errors in the prescription of home medication, preventively suspend this medication and alert the prescribing physician so that the error can be solved.

Material and Methods Prospective cross-sectional study from October 2022 to May 2023 in a tertiary level hospital. Potential errors in their electronic prescriptions were detected using an electronic program linked to the patients‘ home prescriptions. Errors and reasons for suspension of treatment were classified: incorrect dosage (1), treatment completed and not discontinued (2), incorrectly withdrawn treatment (3), incorrect presentation (5) and therapeutic duplicity (6).The interventions carried out in which the deadline for modification of the interventions by the prescribers expired (2 weeks) were also taken into account (4). Treatments and medical services involved were analysed. Average number of days between the detection and notification of the error and its resolution by the prescriber was also evaluated. The e-prescribing system was used as well as a micro-strategy data analysis system.

Results 340 potential home prescribing errors were detected of which 190 (55.9%) were real. 98 (51.58%) were women with a median age of 63 [20–73]. Of these patients 81 (42.63%) were polymedicated with 10 drugs and 34 (41.97%) had at least 15 or more drugs prescribed. The average number of drugs prescribed was 8 [4–13]. Most frequent errors were detected in: semaglutide (28.5%), triptorelin (15%), methotrexate (12.5%), denosumab (9%), aledronic (9%), leuprorelin (5%), dulaglutide (5%), ibandronic (4.7%), risedronic (3%), paliperidone (3%), aripiprazole (2.5%), lanreotide (1.5%) and estradiol (1.3%). The medical specialties with the highest number of prescription errors were rheumatology (31%), endocrinology (28.5%), cardiology (10%), oncology (7.3%) and urology (7.3%). An average of 7 [4–11] days was observed between precautionary annulment and correction of the error. The causes of preventive discontinuation of treatment were type 1 (74%), type 6 (11%), type 4 (6%), type 5 (9%). After the intervention, 98 treatments (51.57%) were discontinued for various reasons: 1 (30.6%), 6 (21.5%), 4 (16.3%), 2 (15.3%), 5 (15.3%) and 3 (1%).

Conclusion and Relevance Electronic communication of discontinuation of home treatment is an important functionality with potential to decrease adverse events due to medication errors and also to reduce costs for the healthcare system and for polymedicated patients.

Conflict of Interest No conflict of interest.