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NP-005 Unauthorised medication use in Estonian hospitals
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  1. Anette Nurm1,2,
  2. Kersti Teder1,2,
  3. Janne Sepp1,3
  1. 1University of Tartu
  2. 2Tartu University Hospital Pharmacy
  3. 3Estonian State Agency of Medicines

Abstract

Background and Importance Unauthorised medication use is often inevitable in Estonia owing to the small local pharmaceutical market, supply difficulties etc. Due to the absence of Summary of Product Characteristics in Estonian language and foreign language package of unauthorised medications, several problems related to the use of these medications may arise. However, no research on this topic has been carried out in Estonia.

Aim and Objectives The aim of this study was to find out how much and which unauthorised medications were used in Estonian hospitals in 2019–2020. The objective was to find out: 1) How many packages of unauthorised medications were used; 2) Which were the most used Anatomical Therapeutic Chemical (ATC) groups; 3) What was the most used active ingredient; 4) What were the most used administration routes and dosage forms.

Materials and Methods Data regarding the use of unauthorised medications in Estonian hospitals in 2019–2020 were obtained from the Estonian State Agency of Medicines and was analysed by the number of packages using Microsoft Excel software.

Results 286 719 and 313 793 packages of unauthorised medicines were used in 2019 and 2020, respectively, which constitutes approximately 12% of all imported medications in Estonian hospitals in both years. The most used ATC-groups in 2019–2020 were anti-infectives for systemic use, nervous system and alimentary tract and metabolism. The most used active pharmaceutical ingredient was oxacillin in both years. Unauthorised medications in hospitals were administered mainly parentally (approximately 75% of all packages) and the most used dosage form was solution for injection.

Abstract NP-005 Figure 1

The number of packages of unauthorised medications issued to hospital pharmacies in 2019–2020, arranged by ATC-groups

Conclusion and Relevance The importance of this work lies in studying the use of unauthorised medications use for the first time in Estonia, similar studies in other countries were not found. As a result of this study, we have information on which unauthorised medications are used the most in Estonian hospitals. Therefore it is possible to improve handling of these medications, for example using labels on packages with the most important information about the specific medication in Estonian language.

Conflict of Interest No conflict of interest.

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