Background and Importance The new model of pharmaceutical care in nursing homes consists of creating drug deposits linked to hospital pharmacy services where hospital pharmacists have the responsibility to provide pharmaceutical care. Besides, polypharmacy is commonly defined as the number of medications taken concurrently using standard cut-offs, but several studies have highlighted the need for multidimensional assessment.

Aim and Objectives The aim of this study is to identify polymedicated residents at risk. For this goal, it is proposed to design a score based on medication indicators.

Material and Methods A score is designed based on demographic data and hazardous drugs for elderly people: age, sex, number of total and chronic prescriptions (Np, Npc), number of prescriptions for: proton pump inhibitors (PPI), cardiovascular drugs (CRZ), vitamin K antagonists (VKA), oral anticoagulants (ACOD), platelet antiaggregant [IGG1] (PAA), neuroleptics (NLP), benzodiazepines (BZD), antidementia drugs (DEM), antidepressants (DEP), opioids (OPI), drugs with high and low anticholinergic effect (Aca, Acb) and concomitant use of NLP, BZD, DEP and DEM (POKER). The weight of each indicator is adjusted according to bibliography and expert opinion.

Results The tool is applied for a population of 3,010 people from 25 centres. More than 90% of the population obtains a result less than 0.6 (2,731 people), 9.5% of the population obtains a result more than 0.6 (288 people) and 1.3% more than 0.9 (39 people).

A practical example: two people with the same number of total prescriptions (15) and chronic prescriptions (12) but with differences in the number of prescriptions per group, have a different score: >0.9 the first one and <0.5 the other one.

Conclusion and Relevance This tool could give us a score that allows to distinguish the risk associated with polypharmacy based on the amount of prescriptions and prescripted hazardous drugs. In the future, it will be necessary to design a study that collects events prospectively, so each indicator could be assigned a weight corresponding to its risk.

References and/or Acknowledgements 1. Carr E, Federman A, Dzahini O, Dobson RJ, Bendayan R. A multidimensional measure of polypharmacy for older adults using the Health and Retirement Study. Sci Rep. 2021 Apr 22;11(1):8783. doi: 10.1038/s41598-021-86331-x. PMID: 33888728; PMCID: PMC8062687.

Conflict of Interest No conflict of interest.