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High-dose quetiapine and therapeutic monitoring
  1. Hervé Javelot1,
  2. Francis Rangoni2,
  3. Luisa Weiner3,
  4. Bruno Michel4
  1. 1Service de Pharmacie Clinique, Etablissement Public de Santé Alsace Nord, Brumath, France
  2. 2Pôle G07, Etablissement Public de Santé Alsace Nord, Brumath, France
  3. 3Psychiatry II, Civil Hospital, CHU Strasbourg, Strasbourg, France
  4. 4Service de Pharmacie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France
  1. Correspondence to Dr Hervé Javelot, Service Pharmacie, Etablissement Public de Santé Alsace Nord, Brumath 67170, France; herve.javelot{at}ch-epsan.fr

Abstract

Quetiapine is an atypical antipsychotic with a good safety profile permitting its administration beyond the maximum dose of 800 mg/day. We report the case of a patient with a resistant schizophrenia treated with high doses of quetiapine (up to 2000 mg/day) combined with drug monitoring and with favourable therapeutic response and tolerance.

  • psychiatry
  • therapeutic drug monitoring
  • antipsychotics
  • quetiapine
  • resistant schizophrenia

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