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Errors in prescribing injectable anticancer drugs: benefits of a pharmaceutical long-term monitoring to improve patient safety in a European comprehensive cancer centre
  1. Mathilde Dupre1,
  2. Laurence Escalup1,
  3. Sandy Blondeel-Gomes2,
  4. Pauline Vaflard3,
  5. Romain Desmaris1,
  6. Paul Cottu3,
  7. Alexandre Acramel1,4
  1. 1Pharmacy, Institut Curie, PSL Research University, Paris, France
  2. 2RadioPharmacology, Institut Curie, PSL Research University, Paris, France
  3. 3Oncologie Médicale, Institut Curie, PSL Research University, Paris, France
  4. 4CiTCoM, UMR8038 CNRS, U1268 Inserm, Université Paris Cité, Paris, France
  1. Correspondence to Dr Alexandre Acramel, Pharmacie, Institut Curie, Paris 75005, France; alexandre.acramel{at}


Objectives We aimed to assess the impact of pharmacist interventions on injectable chemotherapy prescription and the safety of early prescription practice in an adult daily care unit.

Methods Prescription errors were recorded before and after implementing corrective measures. Errors identified from the pre-intervention period (i) were analysed to identify areas for improvement. During the post-intervention period (ii) we compared the errors in anticipated prescription (AP) with those in real-time prescriptions (RTP). We performed Chi-square statistical tests (α=0.05).

Results Before implementing corrective measures (i), 377 errors were recorded (ie, 3.02% of prescriptions). After the implementation of corrective measures (ii), there was a significant decrease in errors, with 94 errors recorded (ie, 1.20% of prescriptions). The error rate in AP and RTP groups was 1.34% and 1.02%, respectively, without a significant difference between the two groups.

Conclusions This study highlights the importance of prescription review, as well as collaboration between pharmacists and physicians, in reducing prescription errors, whether these prescriptions were anticipated or not.

  • Antineoplastic agents
  • Quality Assurance, Health Care
  • Safety

Data availability statement

Data are available upon reasonable request.

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