RT Journal Article SR Electronic T1 Assessment of adherence to printed guidelines for antimicrobial drug use in a university hospital JF European Journal of Hospital Pharmacy JO Eur J Hosp Pharm FD British Medical Journal Publishing Group SP 113 OP 117 DO 10.1136/ejhpharm-2014-000533 VO 22 IS 2 A1 Nives Radošević Quadranti A1 Branislava Popović A1 Ivana Škrobonja A1 Nataša Skočibušić A1 Vera Vlahović-Palčevski YR 2015 UL http://ejhp.bmj.com/content/22/2/113.abstract AB Objectives To assess the quality of antimicrobial prescribing and the level of adherence to the guidelines in the department of medicine at a university hospital.Methods A point prevalence survey was conducted between September 2008 and May 2011 at four selected time points. Demographic and relevant clinical patient data for those receiving antibiotic treatment were recorded. The necessity of antimicrobial treatment was assessed according to a scoring system based on the presence of signs and symptoms of an infection. Antibiotic use was judged according to Guidelines for hospital antimicrobial drug use published in December 2008.Results The percentage of patients receiving antimicrobials varied from 30.8% (N=73) (September 2008) to 25.1% (N=60) (May 2011). At the first time point, 37.3% (N=25) of patients received antimicrobial therapy that was not necessary significantly more often than at other time points (p<0.01). Level of adherence to the guidelines varied between 35.0% (April 2009) and 50.0% (May 2011). The highest level of non-compliance with the guidelines was observed when cefuroxime, ceftriaxone and ciprofloxacin were prescribed.Conclusions Our study demonstrates a continuous overuse of broad-spectrum antibiotics. A decrease in unnecessary antibiotic use and an increase in treatments based on susceptibility testing were noted in the periods when the guidelines were in use. This speaks in favour of guidelines for antimicrobial treatment being a valuable part of antimicrobial stewardship programmes.