TY - JOUR T1 - Occupational exposure to conventional antineoplastic drugs: can it be further limited? JF - European Journal of Hospital Pharmacy JO - Eur J Hosp Pharm SP - 251 LP - 252 DO - 10.1136/ejhpharm-2019-002165 VL - 27 IS - 5 AU - Nicolas Simon AU - Pascal Odou AU - Bertrand Décaudin AU - Pascal Bonnabry AU - Sandrine Fleury Souverain Y1 - 2020/09/01 UR - http://ejhp.bmj.com/content/27/5/251.abstract N2 - In 2019, we celebrated the 40th anniversary of the famous article published by Falck et al, dealing with the mutagenicity of the urine of nurses who were in daily contact with conventional antineoplastic drugs.1 Since the publication of this article, highlighting the hazard of handling such drugs, extensive literature has flowed, in order to:identify the different sources of contaminationcharacterise the risks associated with this occupational exposureevaluate the levels of contaminationassess new technologies/work processes and organisations contributing to limit the spread of contaminationassess different decontamination solutions.All this knowledge has raised our level of vigilance on this issue and encouraged us to upgrade our practices constantly. Scientific data have been obtained through technological advances and in many different operating conditions, the latter making it difficult to define a fair protection level. Moreover, a lack of relevant clinical references and toxicological values has led to a continuous exploration for protective measures. Forty years after the first report of … Correspondence to Dr Nicolas Simon, GRITA Grp Rech Formes Injectables, LILLE Cedex 59006, France; nicolas.simon{at}univ-lille.fr ER -