PT  - JOURNAL ARTICLE
AU  - Johannes Anthon Kroes
AU  - Sander Wilhelm Zielhuis
AU  - Carina Bethlehem
AU  - Anneke Ten Brinke
AU  - Eric Nico Van Roon
TI  - Administration of benralizumab in a patient with severe asthma admitted to the intensive care unit with COVID-19 pneumonia: case report
AID  - 10.1136/ejhpharm-2020-002660
DP  - 2021 Apr 21
TA  - European Journal of Hospital Pharmacy
PG  - ejhpharm-2020-002660
4099  - http://ejhp.bmj.com/content/early/2021/04/21/ejhpharm-2020-002660.short
4100  - http://ejhp.bmj.com/content/early/2021/04/21/ejhpharm-2020-002660.full
AB  - A patient with severe asthma on benralizumab therapy was admitted to the intensive care unit (ICU) for a coronavirus disease 2019 (COVID-19) infection. At the end of the 8 week benralizumab dosing interval, discussion arose as to whether benralizumab should be administered or if treatment should be discontinued, due to the lack of experience with benralizumab in this situation. Severe broncho-obstruction developed, and the next injection of benralizumab was administered during ICU admission without detrimental symptoms. With this case report, we would like to share our experience with the safe administration of benralizumab during COVID-19 pneumonia, guiding doctors in future decision making.All data relevant to the study are included in the article