TY - JOUR T1 - Fixed drug eruption after pentavalent diphtheria, tetanus, acellular pertussis, inactivated poliovirus and <em>Haemophilus influenzae</em> type b combined vaccine in an infant JF - European Journal of Hospital Pharmacy JO - Eur J Hosp Pharm DO - 10.1136/ejhpharm-2021-002875 SP - ejhpharm-2021-002875 AU - Sevil Savaş Erdoğan AU - Filiz Cebeci Kahraman Y1 - 2021/07/06 UR - http://ejhp.bmj.com/content/early/2021/07/06/ejhpharm-2021-002875.abstract N2 - In Turkey, diphtheria-tetanus-acellular pertussis-inactivated poliovirus and Haemophilus influenzae type b (DTaP-IPV-Hib) vaccine has been administered to all children in the second, fourth, sixth and 18th months within the scope of the national vaccination programme. Here we present a rare case of fixed drug eruption (FDE) that occurred as a result of the administration of a pentavalent DTaP-IPV-Hib combined vaccine in a 4-month-old girl. There was no history of taking any other medication before or when the lesion appeared. The lesion responded well to 1 week of topical methylprednisolone aceponate cream application and regressed within 1 week, leaving mild hyperpigmentation. Few cases of FDE have been reported occurring after administration of various vaccines and it is extremely rare in children. To our knowledge, this is the first reported case of FDE developing in an infant after the combined pentavalent DTaP-IPV-Hib vaccine.All data relevant to the study are included in the article or uploaded as supplementary information. ER -