RT Journal Article SR Electronic T1 COVID-19 vaccine triggered autoimmune hepatitis: case report JF European Journal of Hospital Pharmacy JO Eur J Hosp Pharm FD British Medical Journal Publishing Group SP ejhpharm-2022-003485 DO 10.1136/ejhpharm-2022-003485 A1 Merrin Mathew A1 Sheba Baby John A1 Juny Sebastian A1 Mandyam Dhati Ravi YR 2022 UL http://ejhp.bmj.com/content/early/2022/10/12/ejhpharm-2022-003485.abstract AB Autoimmune hepatitis (AIH) is a non-contagious, chronic, inflammatory autoimmune disease in which one’s own immune system attacks healthy, normal hepatic cells. The exact cause of AIH is unknown; however, the combination of genetic, environmental (eg, drugs and natural infection) and immunological factors may lead to AIH. AIH may also be potentiated with the use of vaccines: this case reports one such event following immunisation, along with 1 year of follow-up. A female patient in her late 20s presented to the hospital with yellowish discolouration of eyes, urine and stools. Her medical history revealed that she had been vaccinated with the first dose of a COVID-19 vaccine 10 days earlier. She had a history of asymptomatic COVID-19 infection 3 months ago and a history of chronic analgesic consumption for migraine. She was diagnosed as having AIH through extensive clinical and laboratory workup. This case may be an immediate enhancement of a hidden autoimmune disorder triggered by the vaccination. This adverse event following immunisation has an adequate temporal relationship with her COVID-19 vaccine. The causality can be categorised as ‘indeterminate’ and may be considered as a potential signal following COVID-19 vaccination.