PT  - JOURNAL ARTICLE
AU  - Lv, Mengen
AU  - Xu, Qing
AU  - Ye, Xianfei
AU  - Yu, Qian
TI  - Sulperazon-induced acute reactive thrombocytopenia during treatment of systemic lupus erythematosus: a case report
AID  - 10.1136/ejhpharm-2021-002999
DP  - 2023 Jul 01
TA  - European Journal of Hospital Pharmacy
PG  - e18--e18
VI  - 30
IP  - 4
4099  - http://ejhp.bmj.com/content/30/4/e18.short
4100  - http://ejhp.bmj.com/content/30/4/e18.full
SO  - Eur J Hosp Pharm2023 Jul 01; 30
AB  - The purpose of this study is to report a patient who developed acute reactive thrombocytopenia while undergoing treatment with sulperazon for systemic lupus erythematosus (SLE). Sulperazon is a broad-spectrum antibiotic that can act against a wide range of microorganisms, but rarely causes severe thrombocytopenic events. We describe a 62-year-old man with new-onset acute reactive thrombocytopenia who experienced a precipitous fall in the platelet count from 168×109/L to 1×109/L within 29 hours after exposure to sulperazon. Sulperazon was immediately discontinued followed by administration of intravenous immunoglobulin for six consecutive days. The platelet count eventually recovered and petechiae at the injection sites improved. No complications secondary to acute reactive thrombocytopenia were observed except petechiae.All data relevant to the study are included in the article.