Results of the visual compatibility tests between remifentanil hydrochloride and various drugs
Remifentanil hydrochloride 0.12 mg/ml in D5W | Propofol 20 mg/ml | C | ||
Midazolam 1 mg/ml in D5W | C | |||
Furosemide 1 mg/ml in NS | IC* | |||
Heparin sodium 416.7 U/ml in NS | C | |||
Monobasic potassium phosphate 1 mmol/ml | C | |||
Insulin 1 U/ml in D5W | – | C | ||
Propofol 20 mg/ml | C | |||
Midazolam 1 mg/ml in D5W | C | |||
Magnesium sulfate/GS 8 mg/ml in GS | – | C | ||
Insulin 1 U/ml in D5W | C | |||
Propofol 20 mg/ml | C | |||
Midazolam 1 mg/ml in D5W | C | |||
Furosemide 1 mg/ml in NS | IC† | |||
Heparin sodium 416.7 U/ml in NS | C | |||
Magnesium sulfate/RLS 8 mg/ml in RLS | – | C | ||
Insulin 1 U/ml in D5W | C | |||
Propofol 20 mg/ml | C | |||
Midazolam 1 mg/ml in D5W | C | |||
Furosemide 1 mg/ml in NS | C | |||
Heparin sodium 416.7 U/ml in NS | C | |||
Potassium chloride 1 mmol/ml | – | C | ||
Insulin 1 U/ml in D5W | C | |||
Propofol 20 mg/ml | C | |||
Midazolam 1 mg/ml in D5W | C | |||
Furosemide 1 mg/ml in NS | IC‡ | |||
Heparin sodium 416.7 U/ml in NS | C | |||
Magnesium sulfate/GS 8 mg/ml in GS | Insulin 1 U/ml in D5W | C | ||
Propofol 20 mg/ml | C | |||
Midazolam 1 mg/ml in D5W | C | |||
Furosemide 1 mg/ml in NS | IC§ | |||
Heparin sodium 416.7 U/ml in NS | C | |||
Magnesium sulfate/RLS 8 mg/ml in RLS | Insulin 1 U/ml in D5W | C | ||
Propofol 20 mg/ml | C | |||
Midazolam 1 mg/ml in D5W | C | |||
Furosemide 1 mg/ml in NS | C | |||
Heparin sodium 416.7 U/ml in NS | C |
↵* Remifentanil–furosemide: a white precipitate appeared in the 1:1 (with or without agitation), 1:4 and 4:1 solutions after 15, 30 and 120 min, respectively.
↵† Remifentanil–MgSO4/GS–furosemide: a white precipitate appeared in all solutions, after 15 min (1:1:1 and 4:1:4), 60 min (4:1:1), 24 h (1:1:4, 4:4:1) or more (1:4:1, 1:4:4).
↵‡ Remifentanil–KCl–furosemide: a white precipitate appeared in the 4:1:4, 1:1:1, 4:1:1 and 4:4:1 solutions after 15, 60, 120 min and 24 h respectively. The other solutions remained clear.
↵§ Remifentanil–KCl–MgSO4/GS–furosemide: a white precipitate appeared after 15 min (4:4:1:1, 4:1:1:4 solutions), 30 min (1:1:1:1, 4:1:1:1, 4:1:4:4, 4:4:1:4 solutions) and 24 h (4:1:4:1 solution). The other solutions remained clear, but the 1:1:4:4, 1:4:4:1 and 4:4:4:1 solutions showed a lot of little bubbles.
C, compatible; D5W, dextrose 5%; GS, Glucosaline (3.3% dextrose and 0.3% NaCl); IC, incompatible; NS, NaCl 0.9%; RLS, Ringer lactate stocker.