Pharmacological group | Drug | July–Dec 2010 retrospective Total patients (n=600) | March–Nov 2012 prospective Total patients (n=1048) | ||
---|---|---|---|---|---|
n | % | n | % | ||
Analgesic/anti-inflammatory | Meperidine | 1 | 0.8 | – | – |
Antiarrhythmic agents | Amiodarone | 15 | 11.8 | 27 | 17.8 |
Anticholinergic agents | Oxybutynin | 3 | 2.4 | 5 | 3.3 |
Antidepressants | Amitriptyline | 2 | 1.6 | 9 | 5.9 |
Clomipramine | 3 | 2.4 | – | – | |
Fluoxetine | 20 | 15.7 | 5 | 3.3 | |
Antihistamines | Cyproheptadine | 1 | 0.8 | – | – |
Hydroxyzine | 14 | 11.0 | 28 | 18.4 | |
Benzodiazepines | Clonazepam | 12 | 9.4 | 24 | 15.8 |
Chlorazepate dipotassium | 10 | 7.9 | 12 | 7.9 | |
Diazepam | 30 | 23.6 | 22 | 14.5 | |
Flunitrazepam | – | – | 4 | 2.6 | |
Urinary antiseptic agents | Nitrofurantoin | 10 | 7.9 | 9 | 5.9 |
Vasodilators | Pentoxifylline | 6 | 4.7 | – | – |
*In the retrospective study, a total of 10 patients received two potentially inappropriate drugs and one patient received four. In the prospective only one patient received two potentially inappropriate drugs.