Table 3

Pharmaceutical assessment screening tool (PAST) factors for all sampled patients stratified by agreement of pharmacist-documented and expected PALs

Pharmaceutical assessment screening factorsStratified levels of agreement (number (%))*
−10+1+2
N6 (100)20 (100)8 (100)1 (100)
Organ dysfunction
 Kidney2 (33)5 (25)1 (13)0 (0)
 Liver0 (0)1 (5)0 (0)0 (0)
 Heart0 (0)0 (0)0 (0)0 (0)
 Lung0 (0)0 (0)0 (0)0 (0)
 Bone marrow0 (0)0 (0)0 (0)0 (0)
 Brain0 (0)0 (0)0 (0)0 (0)
Drugs requiring therapeutic monitoring
 Glycopeptide antibiotic0 (0)1 (5)0 (0)0 (0)
 Aminoglycosides2 (33)1 (5)1 (13)0 (0)
 Theophylline/aminophylline3 (50)0 (0)0 (0)0 (0)
 Digoxin1 (17)0 (0)0 (0)0 (0)
 Carbamazepine0 (0)0 (0)0 (0)0 (0)
 Lithium0 (0)0 (0)0 (0)0 (0)
 Ciclosporin0 (0)0 (0)0 (0)0 (0)
 Amphotericin B0 (0)0 (0)0 (0)0 (0)
 Triazole antifungals0 (0)0 (0)0 (0)0 (0)
Number of drugs requiring therapeutic monitoring
 02 (33)18 (90)7 (88)1 (100)
 12 (33)2 (10)1 (13)0 (0)
 22 (33)0 (0)0 (0)0 (0)
Other high-risk medications
 Anticoagulation1 (17)4 (20)0 (0)0 (0)
 Insulin4 (67)4 (20)0 (0)0 (0)
 Opiates1 (17)5 (25)0 (0)0 (0)
 Chemotherapy0 (0)0 (0)0 (0)0 (0)
 Antiretrovirals0 (0)0 (0)0 (0)0 (0)
 Clozapine0 (0)0 (0)0 (0)0 (0)
Number of high-risk medications†
 00 (0)10 (50)7 (88)1 (100)
 12 (33)5 (25)1 (13)0 (0)
 22 (33)5 (25)0 (0)0 (0)
 32 (33)0 (0)0 (0)0 (0)
ICU step-down patient0 (0)1 (5)0 (0)0 (0)
Patient with an infectious disease consult0 (0)0 (0)0 (0)0 (0)
Patient with cystic fibrosis4 (67)1 (5)0 (0)0 (0)
Organ transplant patient0 (0)0 (0)0 (0)0 (0)
Home intravenous therapy0 (0)0 (0)0 (0)0 (0)
Out-of-hospital respiratory service0 (0)0 (0)0 (0)0 (0)
Patient with HIV0 (0)0 (0)0 (0)0 (0)
Patient with Parkinson's disease on apomorphine0 (0)0 (0)0 (0)0 (0)
High-cost medication (not within NHS tariff)0 (0)0 (0)0 (0)0 (0)
Outside competency of attending pharmacist‡0 (0)0 (0)0 (0)0 (0)
Pharmacist-documented PAL
 10 (0)4 (20)0 (0)0 (0)
 26 (100)13 (65)6 (75)0 (0)
 30 (0)3 (15)2 (25)1 (100)
  • *Measured agreement of PALs is the difference of pharmacist-documented PAL minus the expected PAL with a range of values from −2 to +2.

  • †Number of high-risk medications includes drugs requiring therapeutic monitoring plus other high-risk medications.

  • ‡Outside competency refers to documentation by a junior pharmacist that the patient’s complexity is outside the scope of their competency.

  • ICU, intensive care unit; NHS, National Health Service; PAL, patient acuity level.