Prevalence and OR for each flag with its corresponding predictability for the risk of unintentional medication discrepancies (UMDs)
| Flag | Frequency (%) | OR to predict high risk score ≥22 (n=97), p value | AUC predicting risk ≥22 | OR to predict number of UMDs ≥1 (n=126), p value | AUC predicting number of UMDs ≥1 | OR to predict number of UMDs ≥4 (n=30), p value | AUC predicting number of UMDs ≥4 |
| >8 Adm meds* | 140 (56.7%) | 38.7 (14.8, 101.5), <0.0001 | 0.81 | 3.7 (2.2, 6.4), <0.0001 | 0.66 | 8.2 (2.4, 27.8), 0.0007 | 0.69 |
| Diabetic meds* | 53 (21.5%) | 1.8 (1.0, 3.4), 0.05 | 0.55 | 2.4 (1.3, 4.6), 0.007 | 0.57 | 4.0 (1.8, 8.8), 0.0007 | 0.64 |
| Readmit <30 days* | 49 (19.8%) | 4.3 (2.2, 8.4), <0.0001 | 0.62 | 6.8 (3.0, 15.2), <0.0001 | 0.63 | 4.5 (2.0, 10.1), 0.0002 | 0.65 |
| Readmit <7 days* | 69 (27.9%) | 8.1 (4.3, 15.2), <0.0001 | 0.70 | 3.5 (1.9, 6.4), <0.0001 | 0.62 | 4.1 (1.9, 9.1), 0.0004 | 0.66 |
| CCM diabetes | 18 (7.3%) | 3.4 (1.2, 9.3), 0.02 | 0.54 | 2.6 (0.9, 7.7), 0.07 | 0.53 | 5.7 (2.0, 16.1), 0.001 | 0.59 |
| Poor compliance | 16 (6.5%) | 3.7 (1.2, 11.0), 0.02 | 0.54 | 3.1 (1.0, 9.7), 0.06 | 0.53 | 3.7 (1.2, 11.6) 0.023 | 0.56 |
| Age >75 | 82 (33.2%) | 7.7 (4.3, 14.1), <0.0001 | 0.72 | 1.7 (1.0, 2.9), 0.06 | 0.56 | 1.6 (0.7, 3.5), 0.22 | 0.56 |
| Multiple outpatient attendance | 37 (15.0%) | 11.2 (4.5, 28.1), <0.0001 | 0.64 | 1.9 (0.9, 4.0), 0.07 | 0.54 | 1.9 (0.7, 4.8), 0.18 | 0.55 |
| CCM CVD | 12 (4.9%) | 8.4 (1.8, 39.5), 0.007 | 0.55 | 3.0 (0.8, 11.4), 0.11 | 0.52 | 1.5 (0.3, 7.1), 0.63 | 0.51 |
| Age >65 PI M | 22 (8.9%) | 3.0 (1.2, 7.4), 0.02 | 0.55 | 1.4 (0.6, 3.5), 0.44 | 0.51 | 1.2 (0.3, 4.2), 0.83 | 0.51 |
| Freq presenter | 27 (10.9%) | 6.6 (2.5, 17.0), <0.0001 | 0.59 | 0.7 (0.3, 1.6), 0.46 | 0.52 | 1.8 (0.6, 5.1), 0.29 | 0.53 |
| Cardiovascular meds | 20 (8.1%) | 2.5 (1.0, 6.3), 0.06 | 0.54 | 1.5 (0.6, 3.7), 0.41 | 0.51 | 1.3 (0.4, 4.7), 0.69 | 0.51 |
| English difficulty | 10 (4.0%) | 2.4 (0.7, 8.7), 0.19 | 0.52 | 2.3 (0.6, 9.1), 0.24 | 0.52 | 5.4 (1.4, 20.3), 0.013 | 0.55 |
| Outdated pyxis | 195 (78.9%) | 1.2 (0.7, 2.4), 0.50 | 0.52 | 0.6 (0.3, 1.0), 0.07 | 0.55 | 1.4 (0.5, 3.7), 0.56 | 0.52 |
| Anticoagulant meds | 75 (30.4%) | 1.3 (0.8, 2.3), 0.33 | 0.53 | 0.6 (0.4, 1.1), 0.13 | 0.54 | 1.4 (0.6, 3.1), 0.43 | 0.54 |
| Antiepileptic meds | 6 (2.4%) | 1.6 (0.3, 7.9), 0.59 | 0.51 | 0.5 (0.08, 2.6), 0.39 | 0.51 | 3.8 (0.7, 21.6), 0.13 | 0.52 |
| CCM CHF | 3 (1.2%) | 3.1 (0.3, 34.8), 0.36 | 0.51 | 1.9 (0.2, 1.4), 0.60 | 0.50 | 3.7 (0.3, 42.0), 0.29 | 0.51 |
| Opioid meds | 13 (5.3%) | 1.3 (0.4, 4.1), 0.61 | 0.51 | 1.1 (0.4, 3.4), 0.85 | 0.50 | 2.3 (0.6, 8.8), 0.23 | 0.53 |
| High risk transfer | 9 (3.7%) | 0.8 (0.2, 3.1), 0.70 | 0.51 | 0.5 (0.1, 1.9), 0.28 | 0.51 | 0.9 (0.1, 7.4), 0.92 | 0.50 |
| TDM meds | 13 (5.3%) | 1.3 (0.4, 4.1), 0.61 | 0.51 | 1.6 (0.5, 4.9), 0.45 | 0.51 | Not applicable | |
| High-risk specialty | 3 (1.2%) | 3.1 (0.3, 34.8), 0.36 | 0.51 | 0.5 (0.04, 5.3), 0.54 | 0.50 | ||
| Mental health | 1 (0.4%) | Not applicable Not applicable | |||||
| CCM COPD | 1 (0.4%) | ||||||
*Indicates statistically significant flags.
Two flags; no registered GP and prescribing for elderly were not present in study cohort.
Medication classes as per British National Formulary therapeutic classification.
Age>65 PI M is age >65 if patient is from Pacific Island or of Maori descent.
Adm, admission; AUC, area under receiver operating characteristic curve; CCM, chronic care management programme; CHF, congestive heart failure; COPD, chronic obstructive pulmonary disease; CVD, cardiovascular disease; meds, medications; Readmit, readmission; TDM, therapeutic drug monitoring.