Abstract 4CPS-059 Table 1
Cases (n=26)Controls (n=26)P value
Baseline GFR (CKD-EPI, ml/min/1.73 m2) 75.0 (44.8) 70.1 (48.6) 0.709
Linezolid dose (mg/kg) 16.9 (2.8) 17.5 (3.3) 0.479
Cmin, ss (mg/L) 22.6 (14.7) 7.4 (9.0) < 0.001
Subtherapeutic concentrations 0 (0%) 9 (32.0%) 0.002
Supratherapeutic concentrations 20 (80%) 7 (28%) < 0.001
Clinical cure 19 (73.1%) 12 (46.1%) 0.348
Anaemia 7 (28.4%) 6 (24.2%) 0.747
Thrombocytopaenia 13 (52%) 8 (33.3%) 0.187
Final platelet count<100. 000/mm3 18 (69.2%) 4 (16.7%) < 0.001
Discontinuation due to haematological toxicity 5 (19.2%) 1 (3.8%) 0.083