Effect of extraction zone: dosage accuracy and precision attained after suspending a tablet in 10 mL water and extracting a fraction: 1 mL, a tenth of a tablet being the intended dose
| Zone 1, bottom | Zone 5, top | |
| Dispersible Aspirin 75 mg | 83.4±11.1 (71.3–101.3) | 72.5±3.6 (66.7–76.0) |
| Bayer Chewable 81 mg | 44.9±13.9 (27.2–65.4) | 28.8±9.4 (18.5–43.2) |
| Disprin 300 mg | 94.2±8.2* (85.5–105.6) | 86.8±4.2 (80.5–91.0) |
| Aspirin 500 mg | 72.4±88.3 (10.4–209.5†) | 26.2±11.5 (13.3–47.4) |
Per cent of intended dose ±SD (lowest–highest value) (n=6) is given for dose extractions from zone 1 (bottom of dispersion) or zone 5 (top of the dispersion). All samples were agitated (stirred and pumped) before the extraction.
*n=5
†Estimated value, outside validated range.