Table 1.

Evolution in time of renal, hepatic andhaematologic function, and electrolyte balance during sevoflurane treatment

Reference valuesTime (days)
Basal value15306090
Urea (mg/dL)10–5039.162.488.271.152.6
Creatinine(mg/dL)0.2–1.30.910.460.590.610.45
Bilirrubin (mg/dL)0.1–1.31.180.680.871.620.96
AST (U/L)*4–3831.224.219.815.414.2
GPT (U/L)†4–4049.940.241.130.127.4
GGT (U/L)‡8–6159.382989714391578
Sodium (mEq/L)136–145140130131133130
Potassium (mEq/L)3.3–5.14.934.744.744.495.81
Calcium (mg/L)8.4–10.211.211.711.912.612.5
Haemoglobin (g/dL)13–16.512.210.610.28.818.9
Leukocytes (cel/mm3)4.8–10.87.8847.920.536.527.7
Platelets (cel/mm3)130–450184637476382268
INR§0.84–1.161.051.120.990.971.09
TpTA (seconds)¶0.8–1.21.021.040.961.031.08
CRP (mg/dL)**0.0–0.50.4245.622.825.316.5
  • *Aspartate aminotransferase.

  • †Glutamic-pyruvic transaminase.

  • ‡Gamma-glutamyl transpeptidase.

  • §International Normalised Ratio.

  • ¶Activated Partial Thromboplastin Time.

  • **C-reactive protein.