Intervention type | Mortality | Morbidity | Healthcare utilisation | Healthcare costs | Patient satisfaction | QoL |
Reminders | 4 RCTs | 5 RCTs | 2 RCTs | 2 RCTs | 2 RCTs | |
Simplified dosing | 2 RCTs | 2 RCTs | 2 RCTs | 3 RCTs | ||
Direct observed treatment (DOT) | 1 RCT | 1 RCT | ||||
Patient education | 2 RCTs | 3 RCTs | 7 RCTs | 1 RCT | 1 RCT | 8 RCTs |
Counselling | 1 RCT | 2 RCTs | 1 RCT | 1 RCT | 3 RCTs | |
Web-based programmes | 1 RCT | |||||
Prescribing pharmacists | 1 RCT | 1 RCT | 3 RCTs | |||
Physicians assess to adherence information | 2 RCTs | 2 RCTs | ||||
All RCTs positive result | 2 RCTs positive and 1 RCT negative result | RCTs 50/50 positive/negative result within or between | 3 RCTs positive and 5 RCTs negative result | 2 RCTs negative, 1 RCT positive, or 1 RCT negative and 1 RCT positive/negative result within | All RCTs negative result |
QoL, quality of life; RCT, randomised controlled trial.