Table 2

Interobserver agreement for each group of drugs of the tool

Group of drugs	n	α	β	γ	δ	ppos	pneg	ĸ (95% CI)	PO
A. Alimentary tract and metabolism	200	4	2	6	188	0.50	0.98	0.48 (0.13 to 0.83)	0.96
B. Blood and blood forming organs	200	12	19	3	166	0.52	0.94	0.47 (0.26 to 0.68)	0.89
C. Cardiovascular system	200	10	8	26	156	0.37	0.90	0.28 (0.07 to 0.50)	0.83
D. Genitourinary system	200	5	0	9	186	0.53	0.98	0.51 (0.19 to 0.82)	0.955
E. Musculoskeletal system	100	1	2	1	96	0.40	0.98	0.39 (−0.30 to 1.07)	0.97
F. Nervous system	400	23	18	14	345	0.59	0.96	0.55 (0.39 to 0.70)	0.92
G. Respiratory system	50	0	2	0	48	0.00	0.98	0	0.96

n: Number of total evaluations for each group.
α: Both evaluators scored the criteria for this group as being fulfilled.
β: Evaluator 1 scored the criteria for this group as being fulfilled and evaluator 2 scored the criteria as not fulfilled.
γ: Evaluator 2 scored the criteria for this group as being fulfilled and evaluator 1 scored the criteria as not fulfilled.
δ: Both evaluators agreed the criteria for this group were not fulfilled.
*Inadequate variability between groups.
pneg, proportion of negative agreement; PO, global per cent agreement; ppos, proportion of positive agreement.