Table 5

Conditions with verified stability data for refrigerated storage followed by a minimum run-out period of 24 hours at standard ‘room temperature’ or ‘warmer climate’ conditions

Class	Drug	Dose in 240 mL	Diluent	Refrigerated	Standard room temperature	Warmer climate (34°C)
Penicillins	Amoxicillin	Nil data
	Ampicillin	2.88 g (10 mmol/L NaPO₄buffer)	NS	48 hours	24 hours at 25°C	Nil data
	Benzylpenicillin	7.2–14.4 g (citrate buffer)	NS	7 days	24 hours at 37°C
	Flucloxacillin	12–28.8 g (PO₄ buffer)	NS, SWFI	6 days	24 hours at 37°C
Cephalosporins	Cefepime	5.76 g	5D	7 days	24 hours at ‘room temperature’	Nil data
		24–48 g	NS, 5D, SWFI	7 days	24 hours at 22°C–24°C
	Cefotaxime	Nil data
	Cefoxitin	9.6 g	SWFI	4 days	24 hours at 37°C
	Ceftazidime	Not suitable for infusion due to build-up of pyridine
Carbapenems	Doripenem	Nil data
	Ertapenem	Nil data
	Meropenem	Nil data
Antipseudomonal penicillins	Piperacillin /tazobactam	5.4–21.6 g (Buffer and EDTA)	NS, 5D	28 days	72 hours at 23°C	Nil data
Antipseudomonal penicillins	Ticarcillin /clavulanate	Nil data

5D, 5% dextrose; NS, normal saline; SWFI, sterile water for injection.