Experimental conditions verifying stability of selected antipseudomonal penicillins
| Antipseudomonal penicillins Authors | Studied (C) | Dose in 240 mL | Diluent | Conditions under which >90% stability is confirmed |
| Piperacillin (with tazobactam) | ||||
| Arlicot, N, et al 3 | 10.1–55.7 mg/mL | 2.42–13.37g | NS | 24 hours at 35°C |
| Donnelly, R33 | 22.5–90 mg/mL | 5.4–21.6g | NS, 5D | SEQ 28 days at 5°C then 72 hours at 23°C (buffer and EDTA) |
| Mathew, M, et al 60 | 3.375 g /50 mL | 16.2 g | NS, 5D | 2 days at 25°C |
| Moon, Y S K, et al 61 | 168.75–225 mg/mL | 40.5–54 g | NS, 5D | 24 hours at 25°C |
| Rigge, D C and M F Jones 34 | 45 mg/mL | 10.8 g | NS | 21 days at 25°C (buffer) |
| Viaene, E, et al 20 | 128 g/L | 30.72 g | SWFI | 24 hours at 25°C, and 24 hours at 37°C |
| Voumard, R, et al 40 | 56.25 g/L | 13.5 g | NS | 24 hours at room temperature |
| Ticarcillin (with clavulanate) | ||||
| Arlicot, N, et al 3 | 12.8–160 mg/mL | 3.07–38.4g | NS | 24 hours at 35°C |
5D, 5% dextrose; SWFI, sterile water for injection.