Table 3

Correlation between the variations in blood tacrolimus concentration and blood cell count

RBCHbHtWBCPlt
All patients (n=54)0.616 (<0.001)0.624 (<0.001)0.630 (<0.001)−0.060 (0.667)0.038 (0.785)
BMT (n=14)0.516 (0.059)0.485 (0.079)0.506 (0.065)−0.084 (0.777)0.143 (0.625)
CBT (n=28)0.544 (0.003)0.565 (0.002)0.563 (0.002)0.191 (0.329)−0.056 (0.776)
PBSCT (n=12)0.861 (<0.001)0.874 (<0.001)0.868 (<0.001)−0.354 (0.259)0.165 (0.608)
BW ≥56.2 kg (n=21)0.665 (<0.001)0.687 (<0.001)0.663 (0.001)−0.058 (0.802)−0.017 (0.953)
BW <56.2 kg (n=33)0.591 (<0.001)0.590 (<0.001)0.611 (<0.001)−0.076 (0.673)0.062 (0.731)
Age ≥56.2 years (n=27)0.491 (0.009)0.524 (0.005)0.511 (0.006)0.039 (0.845)−0.054 (0.789)
Age <56.2 years (n=27)0.711 (<0.001)0.703 (<0.001)0.722 (<0.001)−0.106 (0.600)0.219 (0.271)
Male (n=31)0.521 (0.003)0.546 (0.002)0.538 (0.002)0.087 (0.641)−0.094 (0.616)
Female (n=23)0.701 (<0.001)0.696 (<0.001)0.710 (<0.001)−0.088 (0.689)0.126 (0.568)
  • Data are expressed as Pearson’s correlation coefficients, and the p value of each test is presented in brackets. ‘n’ represents the number of analysis points.

  • BMT, bone marrow transplantation; BW, body weight; CBT, cord blood transplantation; Hb, haemoglobin; Ht, haematocrit; PBSCT, peripheral blood stem cell transplantation; Plt, platelet; RBC, red blood cell; WBC, white blood cell.